It is a succulent plant native to parts of Asia and Africa. It is known for its unique four-angled stems and its traditional use in herbal medicine.

Stem is 4 angled, succulent, stores water, with nodes and internodes. The stem four angles give the specific epithet "quadrangularis." Leaves are small, alternate, cordate at base, acute apex, ovate, glabrous, produce tendril from axil for climbing and support. Flowers are small, inconspicuous, green to yellow.

Studies show that the Cissus quadrangularis plant may promote bone health and reduce joint pain. This herb is documented to possess a wide-ranging ethnomedicinal uses in malaria, fever, epilepsy, gout, piles, skin diseases, colic, etc.